MII Technology Assessment Awards

• Targeting Antigen-specific CD4+ T cells for In[1]situ CAR-T Cell Generation for Immunotherapy (Schneck)
• Advancement of a Blood based PD (Parkinsons Disease ) with Novel Analytics for Multi-Factor Readouts for disease staging (Mao)
• Developing a First-in-Class Therapeutic Antibody for Treatment of Type-1 Diabetes (Hu)
• Developing a Novel Single Particle Analyzer for High Resolution and High Content Characterization of Nanoparticle-Based RNA Therapeutics (Hsieh)
• ​​​​​​​Developing a Neural Implant for Patients With Spinal Cord Injury (Manbachi)
• Developing a High-Density Tactile Sensor Array with a Single Output Wire for Medical Rehabilitation (Thakor)
• Development of an Immunotherapy for Prevention and Treatment of Type 1 Diabetes (Hamad)
• Developing a Photoacoustic Imaging Device to Modernize Treatment of Peripheral Nerve Injury (Bell)
• Development of Next-Generation, Brain-Penetrant Anthracycline Chemotherapeutics (Koldobskiy)
• Developing a Microfluidic Platform for Detection of Rare Biomarkers from Non-Invasive Biological Sample Matrix (O’Keefe)
• Development of DNA Nanotubes Containing Doxorubicin that Cross the Blood Brain Barrier to Treat Glioblastoma (Kokkoli)
• Developing a Novel Tool for Diagnosing Epilepsy from Scalp EEG: EPIScalp (Sarma)
• Development of an mRNA Booster for the Treatment of Haploinsufficiency Disorders (Coller)
• Development of an Oncolytic Peptide as a Therapeutic for Rectal Cancer (Popel)
• Developing a Novel Non-Invasive, Biomarker Test to Detect and Distinguish Prostate Cancer from Benign Prostatic Prostatic Disease (Pavlovich)
• Delivery of HIF-1 mRNA to Improve Wound Healing (Harmon)
• AI-powered Surgical Mentor: Ophthalmic Procedures (Sikder)
  Accelerating Signal Processing of Infant Worn Vital Sign Monitor (Sen)
• Development of an Inhalable Nintedanib Nanosuspension Formulation for Treating Fibrotic Lung Disease (Sidhaye)
• Developing Kinetic mRNA Particles to Program CAR Macrophages In Vivo for Cancer Therapy (Mao)
• Developing Novel Gastrojejunostomy Feeding Tube for Rapid Bedside Exchanges (Weiss)
• Development of a Novel immune Stimulating Antibody (ISAC) Conjugate Against CD47 (Suk)
• Developing a Novel Spectral Approach For Remote Risk Stratification and Screening of Colorectal Cancer (Mathews)
• Detection of Strep Throat on a Telehealth Visit Using AI and Smartphone Video: StrepAI (Canares)
• Developing an Oral GCPII Inhibitor for Inflammatory Bowel Disease (Peters)
• Developing DPTIP-P12: an Orally Available nSMase2 Inhibitor for the Treatment of HIV (Rais)
• Developing Biodegradable Nanofiber Funnel Conduit for Targeted Muscle Reinnervation (Tuffaha)
• Development of a Chemical Dissolution Formulation to Facilitate the Breakdown and Drainage of Pancreatic Necrosis (Akshintala)
• Developing Novel Hypoxia Inducible Factor Inhibitor to Treat Pathological Angiogenesis in the Eye (Sodhi)
• Developing Chromobacterium-Based Biopesticide for Mosquito Control (Dimopoulos)
• Developing Splicing-based vectors that enhance the efficacy of gene therapy for retinitis pigmentosa (Ling)
• Developing CODA: A novel Clinical Decision Support System for Identification of Macroscopic Cancerous Regions Within Serial Sections (Wu)
• Developing Next Generation Stem Cell Therapy To Treat Glioblastoma (Green)
• Developing Novel Anti-proteotoxicity Therapeutic Agents Targeting Protein Methylation:  Applications for Neurodegenerative Diseases (Wang)
• Genetic Reprogramming of Tumor Cells In Situ for Systemic Cancer Immunotherapy (Tzeng)
• Management of Unresectable Large Solid Tumors in the Liver by Engineered alpha-particle Radiotherapy (Sofou)
• Developed Accumarker, an innovative tumor cavity localizer.  This tool accurately localizes the borders of tumor cavity and diminishing the risk of excessive radiation. (Haibi)
• Developing a novel platform for rapid point-of-care diagnosis-antimicrobial resistance prediction of sexually transmitted diseases (Wang)
• Developing cytoplasmic transfer cell (CTC) therapy for retinitis pigmentosa treatment (Singh)
• Development of a Non-viral, Redosable Gene Therapy to Treat Wilsons Disease (Kumbhari)
• Developing CorFix: A Software for Medical Diagnosis and Pre-operative Planning for Fontan Surgery (Liu)
• Developing a  Novel Mini-Microscope for High-throughput Neuroimaging Applications and Drug Development: Pixela (Pathak)
• Development of TrkB-antagonist ANA12 as novel adjunct treatment for refractory seizures in neonates (McArthur)
• Vaso-Lock: Replacing Sutures for Faster, Easier, and Safer Microvascular and Vascular Anastomosis (Kang)
• Developing Microfluidic Assay for Differentiation of Highly Metastatic Breast Cancer Cells (Konstantopoulos)
• Developing ePACStim: Biomarker Driven Adaptive Brain Stimulation System for Parkinsons Disease (Anderson)
• Developing A Precision Medicine Approach for Ovarian Cancer - Spiro Cyclic Guanidine RPN13 Inhibitor (Anchoori)
• Developing a ProTide of 6-Mercaptopurine for Acute Lymphoblastic Leukemia (Lemberg)
• Utilizing a dendrimer conjugated nSMase2 inhibitor to treat Alzheimers disease (Rais)
• Sustained release epinephrine gels for use in Gastrointestinal Endoscopy (Kamal)
• Developing Off-the-Shelf, Biodegradable Small-Diameter Tissue Engineered Vascular Graft for Arterial Conduit (Gerecht)
• Developing B-TACT - Bortezomib targeted chemo therapeutic for treatment of liver cancer (Selaru)
• Development of Bryostatin-1 as a novel remyelinating drug for multiple sclerosis (Kim)
• Developing DifCons: diffuse-light-collecting integrated concentrators for light-weight, low-cost, ubiquitous solar energy (Thon)
• Developing a Novel Sustained Release Therapeutic for Migraine and Facial Aesthetics -  NanoTox (Reddy)
• Developing a Novel Non-invasive Genomic Biomarker for Human Egg Quality (Das)
• Developing a Naturally Derived and Easily Synthesizable PET Tracer for Specific Diagnosis of Bacterial Infections (Jain)
• Developing Itaconate Prodrug JHU-142 to treat Alopecia Areata (Slusher)
• Developing a Novel UAS Drone a Medical Product Transport System (Amukele)
• Developing an AAV strategy targeting TDP-43 splicing repression to treat Inclusion Body Myositis (Wong)
• Developing a MRI-Compatible Functional Cranial Implant for Pump-Assisted Chronic and Direct Medicine Delivery to Treat Neurologic Pathology (Gordon)
• Development of APPX42, a PSA-activated Recombinant Chimeric Molecular Grenade for Metastatic Prostate Cancer (Isaacs)
• OcuGel: Disruptive Technology for Improved Drug Delivery to the Eye (Ensign)
• Engineered bispecific antibodies for targeted inhibition of cancer metastasis (Wirtz)
• Development of Photoacoustic Diagnosis and Monitoring of Perinatal Brain Hypoxic-Ischemic Encephalopathy and Stroke (Graham)
• Developing ultra-thin, high strength, drug-eluting structures for prevention of ophthalmic infection (Parikh)
• Developing EpiWatch:  A mobile health application for epilepsy management (Crone)
• Development of humanized KCNK9 monoclonal antibody for treating KCNK0-expressing malignancies (Laterra)
• Developing epigenetic modulation and induction of synthetic lethality for cancer therapy (Yegnasubramanian)
• Developing kubanda cryotherapy: low-cost cryotherapy device for the veterinary market (Durr)
• Developing novel persister antigen assay for improved detection of untreated and persistent lyme disease (Zhang)
• Developing VecTech: Next generation automated mosquito surveillance tools (Acharya)
• Developing a molecular profiling formalin fixed patient tumor tissue: novel ligation in situ hybridization sequencing (LISH-seq) platform (Larman)
• Developing a high efficiency sensor for diagnosis of real time electrolyte imbalance Cystic Fibrosis Monitoring (Searson)
• Developing vapor sensing technologies based on stabilized organic transistors (Katz)
• Developing SuperPACS: AI Enhanced Tools for Clinical Stratification of Patients at Risk for Cardiac Disease (Ambale Venkatesh)
• Development of T417, a first-in-class inhibitor of the proto-oncognene PBX1 for the treatment of ovarian cancer and other human malignancies (Wang)
• Developing a tool for early prediction of patients with sepsis who will develop septic shock: ShockAlert (Winslow)
• Developing patient derived organoid models (PDO) predicting response to therapy in liver cancer (Selaru)
• Developing a novel technology for determining the personalized optimal ablation targets in patients with atrial fibrillation (AF) and fibrosis (Trayanova)
• Developing a potent rBCG as a therapeutic intervention for nonmuscle invasive bladder cancer (Bishai)
• Developing an inhibitor of neutral sphinghomyelinase2 for the treatment of Alzheimer’s disease (Rojas)
• Developing a novel therapy initially for triple negative breast cancer (TNBC) with potential for use against many other cancers (Semenza)
• Optimization of an improved formulation of Mebendazole for treatment of brain and other cancers (Riggins)
• Developing software for rehabilitation healthcare analytics & prediction (ReHAP) (Gourab)
• Developing a multicomponent inhibition of hypoxia inducible factor to treat ocular neovascularization (Green)
• Developing a minimally invasive theranostic device for brain neurooncology (Manbachi)
• Developing a novel biomarker and ELISA assay for determination of cognitive status in Alzheimer’s disease (Worley)
• Developing a therapeutic to prevent kidney toxicity in prostate cancer patients receiving PSMA-targeted radiotherapy (Slusher)
• Developing a device to more accurately target spine during lumbar punctures (LP) to collect cerebrospinal fluid(CSF) (Moghekar)
• Developing a method to use non-contrast-enhanced MRI and Perfusion index Mapping (Qin)
• Developing a drug, Ethoxyquin-6, for prevention of chemotherapy-induced peripheral neuropathy (Hoke)
• Develop a polyionic papillomavirus-like particles (VLP) for the treatment of prostate cancer (Viscidi)
• Development of Hypoxia Inducible Factor-1 with Polymeric Chitosan Nanoparticles to improve wound healing (Harmon)
• Developing the Corrie Health Digital Platform: Reinventing cardiac recovery (Martin)
• Developing Intra-ART: A novel platform for MRI-guided intra-arterial placement of therapeutic agents to treat brain tumors (Pearl)
• Developing a novel device for effective minimally invasive treatment for urethral strictures (Wright)
• Developing a cohesive robot-ultrasound probe for prostate biopsy (Stoianovici)
• Development of immunoswitch for treatment of metastatic melanoma: a novel immunomodulator approach (Schneck)
• Developing a halofuginone as a disease-modifying therapy for osteoarthritis (Cao)
• Developing a VLM-modified s-Ontak: a second-generation, Treg-depleting immunotherapy (Bishai)
• Developing a cardiac RF ablation lesion assessment system (Karmarkar)
• Developing a first non-invasive ELISA assay for pulmonary arterial hypertension (Everett)
• SMART surgical tools: optical coherence sensor guided microsurgical tools with enhanced surgical fun (Kang)
• “Smart” programmable digital stethoscope (Elhilali)
• Developing a novel blood/sputum diagnostic test for lung cancer (Brock)
• Developing a novel thyroid cancer specific biomarker panel (Umbricht)
• Developing a precision medicine approach for treating a subtype of severe pain called allodynia (mechanical pain)(Bosmans)
• Developing a new class of therapeutic compounds for the treatment of diarrhea predominant irritable bowel syndrome (IBS-D) (Barrow)
• Developing an injectable nanofiber-hydrogel composite for soft tissue reconstruction (Sacks)
• Developing a long-acting therapy for Parkinson’s Disease (Ko)
• Developing an Epigenetic based test for the prediction of postpartum depression in pregnant women (Kaminsky)
• Developing a 5-HT1A-Receptor: Biomarker stratification of patients with suicidal risk during treatment of pediatric depression (Kaplin)
• Developing the Renalert System, a monitor for real time renal perfusion which enables clinicians to prevent acute kidney injury (AKI) (Hogue)
• Repurposing of Cethromycin (QB101) for Malaria Prophylaxis (Sullivan)
• Developing a new, first-in-class therapeutic to treat a heritable form of retinal degeneration called Leber’s congenital amaurosis (LCA) (Bunz)
• Developing a new treatment for the autoimmune rheumatic disease, systemic sclerosis(SSc) (Lee)
• Developing a small molecule PSMA inhibitor to treat Inflammatory Bowel Disease (Hartman-Ph.2)
• Developing an imaging (FBnTP) agent as a biomarker for tumor aggressiveness and response to chemotherapy in early detection (Madar)
• Develop color-coded quantitative brain cancer mapping for real-time, cost-effective surgical guidance. (Li)
• Develop a therapeutic vaccine as a novel treatment for neuromyelitis optica (NMO) (Levy)
• Develop a potent drug with a novel mechanism for the treatment of leukemia and lymphoma (Slusher)
• Develop a novel tool for seizure localization in medically refractory epilepsy (Sarma)
• Developing bifunctional immunostimulatory antibodies for treatment of cancer (Bedi)
• Develop REMS: Robotic ENT Microsurgery System (Taylor)
• Develop codeDNA: Advanced Malware Variant Detection (Breiner)
• Developing biodegradable aAPC particles for cancer immunotherapy (Green)
• Developing a drug to reverse atherosclerotic heart disease in diabetic mice (Chatterjee)
• Develop an adaptive robotic platform for expandable, easy to program collaborative industrial robots (Hager)
• Developing a saliva based rapid diagnostic test for detection of asymptomatic carriers of the malaria parasite (Dinglasan)
• Improve delivery, enhance efficacy, and prolong glutaminase inhibitor drug levels in the tumor with the ultimate goal of improving outcomes for pancreatic cancer patients (Le)
• Developing LiFi enabled 3D Optical Imaging for collision safety and autonomous transportation (Torruellas)
• Improving computer-assisted craniomaxillofacial surgery (Gordon)
• Using cell permeable peptides derived from Pirt2 mutant protein to treat chronic pain (Dong)
• Developing a device that will reduce reoperation rates in breast conserving surgery. (Benkoski)
• Developing a blood test based on methylated gene markers for breast cancer. (Sukumar)
• Developing an inexpensive tool, called FastStitch, to improve the surgical suture process. (Nguyen)
• Creating a device to assess cardiac filling pressure for preventing re-hospitalization for heart failure. (Silber)
• Introduced a diagnostic method for rapid detection of significant coronary heart disease. (McVeigh)
• Developing a cancer targeting agent, which has special relevance in castration-resistance prostate cancer (In collaboration with University of Maryland, Baltimore County). (Laiho)
• Developing a device, called MouthLab, to enable the fast sampling of medical data. (Fridman)
• Developing a new lotion to augments wound healing, improves healing skin quality and reduces scar size. (Walston)
• Developing a polymeric fore sensor that is used with middle ear titanium prostheses to provide feedback to the surgeon. (Francis)
• Developing non-invasive quantitative CT imaging-based alternative that will provide accurate and rapid determination of the functional significance of coronary artery disease. (Lardo)
• Evaluating the efficacy and toxicity of artemisinin dimers in a mouse model and to select the lead   dimer for further development towards clinical studies in humans. (Boger)
• Develop a prototypic nanoparticle based system to mediate redirected lysis by human antigen-specific cytotoxic T lymphocytes, CTL, to tumor cells that would otherwise not be recognized. (Schneck)
• Developing a technology to use autologous volar fibroblasts to create new thick skin at the stump site for amputees. (Kang)
• Commercialize novel chemical exchange saturation transfer (CEST) magnetic resonance imaging  (MRI) biosensors. (van Zijl)
• Developing a peptide-based therapy for acute and chronic diahrreal diseases. (Zachos)
• Developing a more effective treatment for seizures using amino acid therapy. (Hartman)
• Developing a low cost, high speed, wide dynamic range, software configurable, multimodel imaging sensor. (Rizk)
• Developing Standardized Manufacturing and Sterilization of Customized Bio-Bone Scaffolds for Treating Midfacial Bone Defects. (Grayson)

• Developing a Portable Quantum Sensing Device (Ozturk)
• Designing a Shoe for Individuals with Diabetes: The Davis Walker™ (Jamaludeen)
• Developing a Universal Novel Nanoscale Electrode for High Resolution Applications (Ozturk)
• Developing SUMZ: A stormwater utility management system (Hunter)
• Developing LightTrax: a building occupant lighting tracking system (Nyarko)
• Developing technology that offers a cost-effective and environmental friendly alternate to produce biofuel using naturally available sea water and the sun’s energy. (Early Charm Ventures-Ph.2)
• Developing the iCrystal System and new crystallization platforms for rapid drug treatment. (Aslan-Ph.2)
• Development of a bilateral corneal symmetry 3-D analyzer (Mehravaran)

• Developing a Fiberoptic Arterial Catheter to Measure Real-Time Intravascular Oxygen Saturation and Blood Pressure (Buehler)
• Developing a Novel Medical Device to Non-invasively and Conveniently Monitor Intraocular Pressure (Isaiah)
• Development of a Novel Percutaneous Access Graft for Improved Patient Care (Griffith) 
• Development of a Synthetic Bovine Colostrum as a Unique Anti-Inflammatory and Growth-Enhancing Food Additive for Poultry Farming (Cross) 
• Developing HTLA: A Scalable Platform to Produce Completely Synthetic Gene Therapy Vectors (Li)
• Developing Early identification of shock with a novel point-of-care test for serum renin (McCurdy)
• Third Lung: A Device for Providing Oxygen and Removing Carbon Dioxide without Using the Lungs (Friedberg)
• Development of a small molecule GPR68 inhibitor, a novel therapeutic class for the treatment of acute respiratory distress syndrome (Hong)
• Novel Axin Stabilizer YA6060 is a Promising Therapy for Nonalcoholic Steatohepatitis (NASH) (Shu)
• Developing Antipseudomonal Agent GalSal: A Dual Inhibitor of Pseudomonas aeruginosa Heme Sensing and Iron Uptake (Xue)
• Delivery of the CIB2 Gene to the Retina as a Therapy for Dry AMD (Ahmed)
• Developing the POD-Vis cloud-based platform generates actionable insights from complex clinical datasets (Shulman)
• Developing NEU1-Selective Sialidase Inhibitors for Treatment of Idiopathic Pulmonary Fibrosis (Goldblum)
• Development of the DART Therapeutic Nanoparticle Platform for Fn14-Positive Cancers (Kim)
• Developing a Handheld Point-of-Care Device to Detect Impending Catheter-Associated Urinary Tract Infection (CAUTI) (Srinivasan)
• Developing a Blood Diagnostic for Assessing Head and Neck Cancer Histological Immune Profile (Younis)
• Developing YW2065 with dual activities of Wnt/Beta-Catenin inhibition and AMPK activation for colorectal cancer (Xue)
• Developing novel anti-malarial ART631 as a potential leukemia treatment (Civin)
• Reinventing transplant transportation: teal-time organ management using the HOMAL and COM App (Scalea)
• Developing a novel high-efficacy approach to cancer immunotherapy with minimal toxicity (Davila)
• Developing Elabela into a therapeutic for heart failure (Gong)
• Developing a transseptal puncture device for left atrial access (Gammie)
• Developing a diagnostic for non-small cell lung cancer (Jiang)
• Developing next-generation multi-specific antibody therapeutic (Li)
• Developing a novel bifunctional antibody for lung cancer therapy (Ren)
• Developing a novel transRectal Focal Abdominal Cooling (rFAC) device for the treatment of IRI and SIRS (Hu)
• Developing a blood test for the early detection of lung cancers based on newly-discovered sprRNAs (Mei)
• Using Synthetic Inhibitory Mucin Protecting Lung Epithelia (SIMPLE) technology to treat pseudomonas lung infections (Lillehoj)
• Developing a first-in-class therapy for sepsis (Vasta)
• Developing a portable deficit-adjusted ankle robot for neurologically disabled populations (Macko)
• Optimization and Validation of a Novel Immunotherapy against Clostridum difficile Infection (CDI). (Feng)
• Developing a novel system for recombinant protein expression. (In collaboration with University of Maryland, College Park) (Robb)
• Refining and validating the first universal cancer immunotherapy, At-CAR (Anti-tag Chimeric Antigen Receptor). (Davila-Ph.2)
• Developing a new target and approach to antibiotic therapy (Wilks)
• Using magnetic nanoparticles for the treatment of dental disease (Masri)
• Developing VNLG-152 as a novel targeted therapy for triple negative breast cancer (Njar)
• Developing a technology for Alzheimer’s disease therapy that targets an inflammatory pathway in asymptomatic and symptomatic patients. (Zimmer)
• Develop a method to rapidly assess the function of NKT cells in cancer patients (Webb)
• Developing anti-thrombosis antibody product to improve clinic treatments (Xu)
• Developing a novel hybrid mesh for the treatment of pelvic organ prolapse. (ZSX Medical-Ph.2)
• Developing a technology, called RelaxDetect, which can detect biopharmaceutical aggregation via water relaxation in sealed vials. (Bruce Yu)
• Develop a thermal endoscope for laparoscopy. This technique will reduce serious intraoperative complications by over 50%. (Pearl)
• Commercialization of an Inflammatory Bowel Disease (IBD) diagnostic based on a microbiome signature technology. (ITVMD-Ph.2)
• Developing an interactive web-based software that will be commercialized for detecting and addressing parental psychosocial risk factors for child abuse/neglect within healthcare settings. (Dubowitz)
• Develop a unique opioid analgesic with reduced tolerance. (Coop)
• Developing a topical cream for treatment of cervical intraepithelial neoplasia. (Khanna)
• Developing a device for Noninvasive Detection of Injury-Site Oxygen Deficiency and Excessive Pressure of Compartment Syndrome. (Zhang)
• Developing MyoNOsen; A Novel Oligonucleotide Therapy for Hypertension and its Sequela, Heart Failure (HFpEF). (Fisher)
• Measurement of Reactive Oxygen Species to Assess Red Blood Cell Quality. (Kao)
• Developing the AVAD-2, an Automated Vascular Access Device for Lifesaving Procedures. (Sarkar)
• Developing a Novel, Safe and Protective Zika Vaccine. (Li)

• REVLR™: An Immersive Modeling and Data Visualization Environment (Boot)
• Development of NitraSense™: A Portable Water Quality Analyzer (Kumar)
• Developing “BreathShake”: Next-Generation Breathable Shake Flask (Srinivasan)
• Developing "ScanMaster" - Mirror-Assisted Continuously Scanning Laser Vibrometry for Measuring Three-Dimensional Panoramic Vibrations of Structures (Zhu)
• Harvesting Lithium & Uranium from Landfill Coal Slurries and Brines (Al-Sheikhly)
• FlexiCharge: Flexible Thermoelectric Generator for Wearable Health Monitoring Devices (Madan)
• Developing Heteroduplex Thermostable Ligase Assembly (HTLA): A Rapid and Cost-Efficient Technology to Construct Large DNAs (Bieberich)
• Developing GlucoSense: Binding Protein-Based Biochemistry Analyzer (Rao)
• Developing "TrackingStar" - A Zero-Contact Tracking System for Wind Turbine Health Monitoring (Zhu)
• Developing Energymaster - a Floating Hybrid Tidal/Wave/Wind Energy Harvesting System (Yu)
• Developing GraphCAN: Graph-Based Algorithms for Secure Vehicular Communication (Islam)
• Developing a Data Quality Toolkit (Koru)
• Creating safe and flexible alkaline rechargeable Zn batteries (RZB) (Madan)
• Developing Flex-nucleosides to treat SARS-CoV-2 and COVID-19 (Seley-Radtke)
• Develop 'Transfinity' an Infinitely-variable Transmission for Tidal Energy Harvesting (Zhu)
• Developing a System for Privacy Management Using Condensation-Based Differential Privacy: MITIGATE (Chen)
• Developing a new high-efficiency DNA cloning platform for synthetic biology applications: ExSembly (Li)
• "Windmaster" - an Improved Hybrid Vertical Axis Wind Turbine (Yu)
• Developing a System for Vulnerability IdeNtifiCatIon (VINCI) (Karabatis)
• Developing a NanoQuineTM: Nanoparticle-Encapsulated Antimalarials to Treat Lupus Nephritis (Szeto)
• Building a scalable and intrusion-tolerant permissioned blockchain system (Zhang)
• Developing an innovative three-drug therapy for acute myeloid leukemia (Bieberich)
• Apogee scanner, a laser-based spectrographic system for stand-off detection of trace materials (Arnold)
• Development of bidirectional cannula for arterial access for extracorporeal life support (Griffith)
• Developing DL5016 as an enhancer for cyclophosphamide-based chemotherapeutics (Wang)
• Development of NCGC-43 as a novel fast-acting antidepressant (Thompson)
• Developing a way to detect antibiotic-resistant bacteria in blood (Kostov)
• Developing a novel drag reduction approach for box trailers TrimJET (Farquhar)
• Developing an impact-driven piezoelectric energy harvester: ActiveCharge (Lee)
• LifePower: a self charging power source for implantable devices (Slaughter)
• SolarSafe: a long-lead-time forecaster of solar storms (Savani)
• Developing ‘substrate-cage: devices for novel enzyme discovery (Gardner)
• Developing small molecule pyrimidines potent anticancer therapeutics (Seley-Radtke)
• Developing a commercialization plan for CRAFT cybersecurity system (ITVMD-Ph.2)
• Develop an immunotherapy drug (BiTE) for the treatment of cancer. (Ostrand-Rosenberg)
• Developing an App for real-time audience enhancement and music education during music presentation and concerts. (Dusman-Ph.2)
• Biomarker discovery and validation for Kinase Inhibitors (Bieberich)
• Developing a geared infinitely variable transmission with minimal speed fluctuation. (Zhu)
• Working to increase food safety and agricultural productivity through innovative feed additives. (MycoInnovation)
• Developing soluble CD80 (CD80-Fc) as a therapeutic agent for the treatment of cancer. (Ostrand-Rosenberg)
• Develop and evaluate the efficacy of a recombinant NNV (Nervous necrosis virus) vaccine. (Vakharia)
• Produce a bioamended activated carbon pellet seeded with PCB- degrading microorganisms to reduce the concentration of polychlorinated biphenyls (PCBs) in sediments. (Sowers)
• Developing a sensing system comprising of ultra-low cost textile-based nonrigid capacitive sensor arrays and inertial sensors that allow individuals with upper extremity paralysis to control their appliances and security systems remotely. (Banerjee)
• Developing multi-site TMS Tools for improving Impaired Brain Connectivity. (Choa)
• Development of HoloMentor: eXtended Reality (XR) for Clinical Telementoring. (Mentis)
•  

• Developing a Bioimpedance Capsule System for Monitoring Epithelial Tissues in the GI Tract (Ghodssi)
• Developing a Light-Activatable, Sustained-exposure Ethanol Injection Technology (LASEIT) for Locally Advanced, Unresectable Tumors (Huang)
• Developing Eco-Friendly Soft Materials That Can Absorb Impact and Protect Fragile Objects (Raghavan)
• Development of Tunable Energy Absorbing Materials to Enhance Safety and Crashworthiness (Wereley)
• Development of an Ultra-High Coupling Efficiency Fiber-to-Chip Coupler for Photonic Integrated Circuit (Zhang)
• Developing a Carbon-Sequestration Building Insulation Materials: Recycling Agriculture Waste for Sustainable Thermal Insulation Panels (Ren)
• Creating Quantum Modems and Routers to Build Quantum Networks (Waks)
• Developing a Compact Chip for Laser Injection Locking and Optical Parametric Oscillation (Lu)
• Development of a Dual-Cup Reverse Shoulder Implant (Wang)
• Developing Reliable AI (RELAI): a Platform to Efficiently Design, Train, Inspect and Improve AI Systems (Feizi)
• Employing Smart Underwear in a novel inclusive diagnostic test for SIBO (Hall)
• Developing a Reversible Electro-Adhesion of Hydrogels to Tissues: Enabling Suture-Less Surgeries (Raghavan)
• Creating “Dost”: A Smart Virtual Friend That Can Talk, Interact, and Feel, Just Like You! (Bera)
• Developing IRIS Reads:  A literacy intervention/instruction App that is implemented as a suite of "mini-games" that crosses augmented (AR) and virtual reality (VR) platforms (Bolger)
• Developing Highly Secure Anticounterfeiting Tags with Deep Learning Software for Reliable (Chen)
• Retraining the immune system with lymph node depots to induce durable remission in type-1 diabetes (Jewell)
• Developing an autonomous delivery robot with learning-based dense crowd navigation capabilities (Manocha)
• Developing Artificial Intelligence software for assessment of posture and form in violin instruction (Fermuller)
• Developing Sensitive Hybrid Nanosensors for Meat Freshness Monitoring (Gong)
• Developing capacitive touch cuffs to track hand and finger gestures (Vaughn-Cooke)
• Developing plant gene editing with novel CRISPR-Cas12 systems (Qi)
• Electroformation: A Low-Cost Alternative for 3D-Printing of Biocompatible Hydrogels (Raghavan)
• Managing Integrated Cyber Risk (Harry)
• Manufacturing VacuGlass: Low-cost Vacuum Insulated Windows (Kim)
• Developing a Resonate Pulsating Combustion System for Flow Control Applications (Flatau)
• Developing a Scalable High Power Narrow Linewidth Semiconductor Laser for Self-Driving Car Using FMCW LiDAR (Dagenais)
• Developing a Bacteriolytic Enzymes against Proprionibacterium acnes for Treatment of Acne Vulgaris (Nelson)
• Developing Autothermal Catalytic Wall Reactor for Natural Gas to Liquids (Liu)
• Developing a Shock Synthesis of Nanoparticle Alloys for Ammonia Oxidation (Hu)
• Development of an on-chip microelectrode solution chemistry sensor for liquid cell electron microscopy (Woehl)
• Developing an Integrated Onboard Charger and Smart Control System for Electric Vehicles (Khaligh)
• Developing CATA: Cyber Aptitude and Talent Assessment (Bunting)
• Developing flexible bioelectric sensor for detection and inhibition of biofilm (Ghodssi)
• Staggered electrode multi-battery for emerging on-board power applications (Rubloff)
• Developing MCube: A building energy monitoring, modeling and management software system (Srebric)
• Creating real-time 3D prinitng, quality assurance and product acceptance testing (Schultheis)
• Developing an add-on Brillouin biomechanics module for confocal microscopes (Scarcelli)
• Developing VOLT: a tailored occupation specific language training in immersive virtual reality environments (Bunting)
• Developing a mucosal vaccination against RSV infection (Li)
• Developing a recurrent processing unit (RPU) for high performance computing (Lathrop)
• Building-scale weather and energy forecast service (BuildECast) for electricity savings (Jin)
• Developing novel polyphosphazene technology for stabilizing protein therapeutics (Andrianov)
• Developing targeted enzymes for effective treatment of lysosomal disorders (Muro)
• Developing drought-tolerant crop cultivars with improved water-use efficiency (Xiao)
• Develop QUANTITY: A novel analysis kit for protein drug development (In collaboration with Johns Hopkins University). (Li)
• Developing an integrated power electronic charger/converter for plug-in electric vehicles. (Khaligh)
• Developing an efficient mucosal vaccination mediated by the Neonatal Fc Receptor. (Zhu)
• Creating hemostatic bandages based on a new biocompatible polymer (In collaboration with University of Maryland Baltimore). (Raghavan)
• Developing and testing protocols for scour sensing post deployment. (Tauros-Ph.2)
• Developing novel acyclic cucurbituril molecular containers as broad spectrum reversal agents for neuromuscular block agents used during surgery. (Isaacs)
• Developing a clinical assay that would provide a tool to improve time to diagnose and monitor disease progression in ALS and possibly other neuromuscular diseases (In collaboration with University of Maryland, Baltimore). (Chin)
• Developing a vaccine against a significant swine pathogen, procine reproductive and respiratory syndrome virus (PRRSV). (Zhang)
• Developing 2D hyperspectral imaging techniques for manufacturing yield and device failure analysis for photovoltaic cells and LEDs. (Bartolo)
• Develop a new technology for the production of liposomal nanoparticle drugs in a unique continuous-flow manufacturing process. (DeVoe)
• Develop data analysis tools on a user-friendly web interface and customize them for a variety of clients ranging from national chain restaurants to other establishments and local health departments in searching the existing nationwide food safety inspections database. (Bederson)
• Developing a novel, generalized approach to the formulation of vaccines against Gram-negative pathogens (In collaboration with University of Maryland, Baltimore). (DeShong)
• Customize Behavioral Activation Treatment for Depression (BATD) for a mobile platform to be used by clinicians and their patients by creating a BATD mobile application to be used in conjunction with therapy. (Lejeuz)
• Developing a non-invasive way to evaluate the quality of a donor kidney known as kidney viability assessment system (KVAS). (Chen)
• Engineering an All-natural, Eco-friendly Foam for Highly Efficient Atmospheric Water Harvesting. (Li)
• Machine Intelligence-Accelerated Discovery and Production of All-Natural Plastic Substitutes. (Chen)
   

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